The importance of optimal 25-hydroxyvitamin D levels in the glycemic control of older adults with type 2 Diabetes Mellitus: Data from the study on aging and longevity EELO

Introduction: Optimal serum levels of vitamin D are great importance, especially in populations with comorbidities such as Diabetes Mellitus (DM). Objective: The study evaluated the relationship between hypovitaminosis and glycemic control older adults type 2 DM. Methods: Cross-sectional prospective study, part EELO project (Study on Aging Longevity), conducted Southern Brazil. Glycated hemoglobin (diabetes ≥6.5%) (25(OH)D) were evaluated. Hypovitaminosis was determined using cutoff points <20 <30 ng/mL). Multivariate logistic regression used to assess risk having uncontrolled Results: Of 120 included aged 60 87 years, 74.2% women, 66.7% hypoglycemic medications 75.8% exhibited diabetes. An inverse correlation observed 25(OH)D glycated (rS=-0.19, p=0.037), suggesting that low associated poor diabetic individuals. prevalence when ng/mL 34.2% 75.0%, respectively. odds ratio (OR) analysis showed individuals 25(OH)D<20ng/mL have almost 4 times more DM (OR:3.94; CI95%:1.25-12.46, p=0.02) compared sufficient D. Conclusion: results indicate optimal currently recommended for should preferably be 30 or higher contribute better DM.